Nov 23, 2020
We review the false negative rates of different COVID tests (PCR and rapid antigen), the known knowns and known unknowns of the Moderna vaccine.
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We discuss:
- Why the lack of a legitimate gold standard is a challenge when comparing different tests for COVID-19 [01:45];
- RT-PCR: why we shouldn't be reassured by a negative test result [03:45];
- How your pretest probability of disease affects your interpretation of test results [07:00];
- The COVID antigen test: faster and more widely available, but less accurate [08:10];
- A NYT report of a rapid antigen test study showing suboptimal test sensitivity when applied to asymptomatic people [10:15];
- Why you can’t rely on a negative test to make your decision to travel or spend time with family/friends for the holidays [12:05];
- Whether you need to quarantine if you’ve been in close contact with someone who themselves was exposed to a known COVID patient [13:30];
- The Moderna vaccine which has a reported efficacy of 94.5% [14:00];
- And more.
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